The HPV 16/18 Antigen Test Kit is used for the qualitative detection of HPV 16/18 E6&E7 oncoproteins in female cervical swab specimens. This kit is intended to be used as an aid in the diagnosis of Cervical Pre-cancer and Cancer.
In developing countries, cervical cancer is a leading cause of cancer related death of women, due to the lack of implementation of screening tests for cervical pre-cancer and cancer. A screening test for low resource settings should be simple, rapid, and cost effective. Ideally, such a test would be informative regarding HPV oncogenic activity.
Expression of both HPV E6 and E7 oncoproteins is essential for cervical cell transformation to occur. Some research results demonstrated a correlation of E6 &E7 oncoprotein positivity with both severity of cervical histopathology and risk for progression. Hence, E6&E7 oncoprotein promises to be an appropriate biomarker of HPV-mediated oncogenic activity.


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